University of Wisconsin–Madison
Professor Mukhtar and five scientists sit and talk around a table
Dr. Longley and scientist Tony Xiao studying a computer screen

Skin Disease Research Center Home

The UW SDRC is a collaborative community of scholars including 57 members from 20 departments in six Schools and seven Institutes, all studying cutaneous biology and skin diseases at the UW. Funded by a highly competitive grant from the NIH and bolstered by School and Departmental funds, the UW SDRC leverages more than $4 million in funding to provide facilities, seminars, and seed money to a growing research community.

What Can We Do For You?

  • Cell Culture Preparation and Training

    For a nominal fee, we offer the following cell culture services:

    • Preparation for primary cells and established cell lines for both human and mouse cells
    • 3-D Cultures
    • Lentivirus production and Electroporation
    • Mycoplasma testing with a 24-hour turnaround time
    • Specialty cell culture medium preparation
    • Cell culture training for lentivirus and electroporation productions only

    Download the Cell Culture Order Form and Fee Schedule.

    Email completed order forms to sdrc@dermatology.wisc.edu, or fax to 608-263-5223.

  • Pathologist Services

    The Experimental Cutaneous Pathology Core offers regular access to expert pathologists Core Director B. Jack Longley, MD, and Core Co-Director Ruth Sullivan, VMD, PhD:

    • SDRC Member Slide Review: 2nd and 4th Wednesdays at 9:00am, Room 6525 WIMR II, 1111 Highland Ave (Longley and Sullivan)
    • UWCCC Open Slide Review: Final Mondays at 1:00pm, Room 6525 WIMR II, 1111 Highland Ave (Sullivan)

    Dr. Sullivan offers technical and professional support for histologic analysis of animal models of human disease, especially rodent models. She will provide animal pathology consulting services, including diagnostic evaluation, in concert with dermatopathologist Dr. Longley.

  • Skin Sample Library

    The Experimental Cutaneous Pathology Core has a library of skin specimens available to researchers interested in skin biology, including:

    • Normal human skin (identified and de-identified)
    • Samples of various human skin diseases (identified and de-identified)
    • Fresh tissue samples, in addition to formalin-fixed parraffin-embedded tissue samples.

    See the section below for information on Histology, IHC, and in situ hybridization services.

    To order tissue slides and samples, fill out the Tissue Request Form and send to sdrc@dermatology.wisc.edu.

  • Histology, Immunohistochemistry/In situ Hybridization

    The Experimental Cutaneous Pathology Core offers the following Histology/IHC/ISH services:

    • Routine histology services ranging from specimen processing & embedding to special stains
    • Immunohistochemistry and in situ hybridization for new and established antigens, with standardization of results through automation
    • Normal and benign formalin-fixed paraffin-embedded control tissues

    To order tissue slides and samples, fill out the Tissue Request Form and send to sdrc@dermatology.wisc.edu.

    To order IHC services, fill out the IHC Request Form and send to sdrc@dermatology.wisc.edu.

  • Tissue Micro Array Construction

    The Experimental Cutaneous Pathology Core can build TMAs from formalin-fixed, paraffin-embedded tissue blocks to your research needs.

    Requests for TMA construction require consultation: Please submit a summary including a scientific basis for your project, a brief description of what your project needs are, and your source of funding to Megan Maguire at sdrc@dermatology.wisc.edu.

    Prices vary depending on the scope of your project.

  • inForm TissueFinder Advanced Image Analysis Software

    The Experimental Cutaneous Pathology Core offers access on a reservation basis to the latest version of inForm® Tissue Finder™ Advanced Image Analysis Software from PerkinElmer for research pathology.

    This software is used to analyze images obtained from any Nuance™ or Vectra™ multispectral imaging system.

    • Request Access (download form): You must be trained and designated by your PI as an authorized user in order to use our software. Please download and submit the linked access request form.
    • Make a Reservation (link – UW NetID login required): Authorized users may reserve time for self-service use of the software. Click the link to be redirected to our scheduling app.
      • The scheduler sends notification of your reserved time to the email address linked to your NetID.
      • You will be billed for the time you reserve, rounded to the nearest quarter-hour based on your login times.
      • Hourly rates are listed in the table below.
    • Location: Our software station is located in the ECPC Laboratory, Room 402 SMI, 1300 University Ave.

    We offer training sessions and hands-on technical assistance to researchers interested in using the software. Please send any requests for training and assistance to Megan Maguire at sdrc@dermatology.wisc.edu.

    Hourly rates:

    inForm® Tissue Finder™ software Non UW SDRC Member UW SDRC Member
    Self-Service $26/hour $18.20/Hour
    Assistance provided by ECPC personnel $35/hour $35/hour
    Assistance provided by pathologist $100/hour $100/hour
  • Pilot Grant RFP

    We fund pilot projects through the Pilot and Feasibility Studies Program!

    This year’s RFA is now closed. Thanks for the excellent response. We will open the 2019 application cycle in January, 2019 so check back often! If you have questions, contact Megan Maguire at sdrc@dermatology.wisc.edu.

  • Become a UW SDRC Member

    To become a member of the UW SDRC, Please submit the following to sdrc@dermatology.wisc.edu:

    1. A current CV or biosketch
    2. A paragraph outlining dermatology-specific research purposes (dermatology-related personal statement included with a biosketch would satisfy this requirement).

    Material will be evaluated by the UW SDRC Executive Committee for final approval.

    Please see the Members page for more details.

  • Donate to the UW SDRC

    Our research supports the clinical and academic missions of the University of Wisconsin-Madison School of Medicine and Public Health. Your financial support helps us in our search for treatments and cures for rare and common skin diseases.

    Please see the Donate page for ways you can contribute to our work!

    If you would like to discuss specifics about giving to Dermatology, please contact our administrative office by calling 608-287-2620 and ask for our Department Administrator or Department Chair, or send an email.