The Department of Dermatology – RIME/SJS Study

Clinical, Immunologic, and Genetic Characterization of Severe Mucocutaneous Reactions

About the Study

We are working on a research project to understand why some people get severe blistering skin reactions following infections. We hope by better understanding the cause we can provide better treatment for patients and prevent these reactions from occurring and recurring. This study involves collection of medical information, photographs and optional samples of saliva, blood and tissue.

If your doctor or advanced practice practitioner has diagnosed you with a severe mucocutaneous reaction and you would like to learn more about this research study, please complete the form below and we will contact you about the project.

You may be eligible to participate in this study if:

  1. You are an individual of any age from infant to adult
  2. You have a diagnosis of severe mucocutaneous reactions or related disorders including:
    1. Reactive infectious mucocutaneous eruptions (RIME)
    2. Mycoplasma-induced rash and mucositis (MIRM)
    3. Erythema multiforme (EM)
    4. Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)
    5. Other disorders on this spectrum

Participants with recurrent disease should have at least one episode that was diagnosed by a dermatologist or pediatric dermatologist

What would this study involve?

  1. Providing access to your medical records to the study team
  2. Optional: Providing saliva, blood or tissue sample
  3. If you are a study candidate please complete the survey form HERE

Meet The Study Investigators

Beth Drolet, MD

Position title: Professor and Chair, Geneva F. and Sture Johnson Distinguished Chair

Yvonne Chiu, MD

Position title: Medical College of Wisconsin

Erin Mathes, MD

Position title: University of California, San Francisco

Irene Lara-Corrales, MD, M.Sc.

Position title: Hospital for Sick Children, University of Toronto

Michele Ramien, MD, FRCPC, DABD

Position title: University of Calgary


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Christina Sheehan – Clinical Research Supervisor
Dept. of Dermatology
Ph: 608-287-2622
Fax: 608-287-2693

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Maya Muldowney – Clinical Research Fellow
Dept. of Dermatology
Ph: 608-287-2622
Fax: 608-287-2693