Our Labs
Quick Facts
10 Principal Investigators
$18M active grants, incl. $10M from NIH
7 Endowed professorships
7 Research labs
5 Active VA Merit Rev. Awards
Presentations
Video library of our recent online presentations and talks.
Contact
Basic Research Admin.
Dept. of Dermatology
dermresearch@dermatology.wisc.edu
About Our Labs
Basic research faculty in the Department of Dermatology study a wide range of dermatological disorders, including skin cancers and non-cancer skin diseases such as Psoriasis, depigmentation, and skin discoloration.
Research targets in our labs range from cellular mechanisms of disease progression and drug resistance to patient presentation in a clinical setting, and our researchers are investigating new uses for current drugs such as anti-inflammatories, as well as the use of plant-based chemicals for chemoprevention.
Our world-renowned researchers are supported by grants from the Dermatology Foundation, the National Institutes of Health, the Department of Veterans Affairs, the Department of Defense and several other non-profit organizations and companies.
Research Topics by Lab
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All Labs
- Melanoma development and progression
- Use of plant-based chemicals for chemoprevention
- Role of Plk1 in Cancer
- Role of SIRT1 in Cancer
- Chemoprevention of Cancer by Resveratrol
- Frizzled6 signaling in hair orientation control
- Astrotactin2 in PCP and development
- Melanoma development and progression
- Blastic plasmacytoid dendritic cell neoplasm
- Depigmentation
- Skin discoloration
- Establishing mastocytosis as an oncogene driven neoplasia
- Discovery and characterization of the intracellular-juxtamembrane class of KIT activating mutations
- Discovery of human epidermal keratinocyte KIT ligand and creation of humanized K14-KIT ligand transgenic mice with epidermal melanocytes
- Cutaneous T-cell lymphomas
- Cellular mechanisms of disease progression and drug resistance
- Phenotypic plasticity and drug-resistance
- Metabolic dynamics during cancer progression
- Targeting the mitochondrial stress response
- Melanoma development and progression
- Cellular mechanisms of disease progression and drug resistance
- Melanocyte biology
- Melanoma development and progression
- Patient presentation in a clinical setting
Labs by Research Topic
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Labs by Topic: Skin Cancer
Labs by Topic: Non-Cancer Skin Diseases
Labs by Topic: Research Target
Research News
Clinical trial repurposes cancer drug for treatment of vascular malformations
Beth Drolet, chair of the Department of Dermatology at the University of Wisconsin School of Medicine and Public Health, is motivated by the stories of the pain and disfigurement that some of her patients experience.
May 25, 2021Faculty Highlight: Gloria Xu, MD, PhD
Curing Cancer With A Surgeon’s Knife A micrographic surgeon, Gloria Xu, MD, PhD, is building a library of skin cancer samples that can be used by fellow researchers to seek out innovative therapies and medicines. …
February 22, 2021Faculty Highlight: Stefan Schieke, MD
“While we have known for a very long time that your diet affects your body and health, we are only beginning to appreciate that the same is true for the cells and their choice of fuel within our body.”
July 3, 2020- More Research News posts
Recent Publications
See what we're publishing! Our clinical and research faculty and their staff publish their research in a variety of top-tier journals.
Active Research Grants
See what we're working on! We receive funding from federal, state, and private sources.
Research Faculty
Nihal Ahmad, PhD
Position title: Professor and Vice Chair for Research, Dermatology Research Laboratories
Gary Wood, MD
Position title: Professor and Founding Chair, Geneva F. and Sture Johnson Professor Emeritus
To Heal
Our Mission
To Educate
To Discover