Thomas D. Keenan, MD, PhD
Position title: Assistant Professor and Director of the Dermatology Consult Service
2011 Mayo Medical School, Rochester, Minnesota
MSTP – M.D./Ph.D.
2001 Boston University, Boston, MA
Biology, Magna Cum Laude B.A.
2016 Dermatology/Internal Medicine University of Wisconsin Madison
Membership and Honorary/Professional Societies
American Academy of Dermatology 2011-present
American Medical Association 2003-present
Medical School Honors / Awards
Virginia Ott Kieckhefer Physician/Scientist Scholarship 2003-2011
Peer Reviewed Journal Articles/Abstracts
Smith SB, Geske JB, Keenan TD, Zane NA, Maguire JM, Morgenthaler TI. Morbid Obesity Is Associated With Delayed Diagnosis and Management of Acute Pulmonary Embolism. Chest. October 2010, Vol 138, No. 4_MeetingAbstracts
Keenan TD, Radhakrishnan S, Bell M, Barry M, Pease LR. Retargeting IgM Antibodies with Different Specificities to a Common Cell Type Reveals Shared Mechanisms Regulating Cellular Activation. J. Immunol. 2009 Apr; 182(91): 12.
Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA.. Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.. Haematologica. 2004 Dec; 89(12): 1459-67.
Cardoso AA, Keenan TD, Veiga JP, Tse, WT, Sallan SE, Guinin EC, Nadler LM.. Leukemia milieu differentiates bone marrow mesenchymal stem cells into stromal-like cells that support leukemia cell survival.. Blood. 2001 Nov; 98(11): 764a.
Barata JT, Cardoso AA, Keenan TD, Sallan SE, Nadler LM, Boussiotis VA. Downregulation of p27kip1 by IL-7 is mandatory for induction of bcl-2, promotion of viability and cell cycle progression in T cell acute lymphoblastic leukemia cells. Blood. 2000 Nov; 96(11): 462a.
Veiga JP, Keenan TD, Barata JT, Sallan SE, Nadler LM, Cardoso AA. Peroxisome proliferators-activated receptor-y (PPAR-y) expression by bone marrow endothelium reveals a potential target for therapeutic intervention in acute lymphoblastic leukemia. Blood. 1999 Nov; 94(Suppl. 1): 627a.
Keenan TD. (2009, October 1). Elucidation of the Activation Mechanism of the Human IgM hIgM12. Thesis, Mayo Clinic College of Medicine.
Keenan TD, Rush P, Williams E, Bennett D. (May 2014). Blastic Plasmacytoid Dentritic Cell Neoplasm. Poster presented at: Wisconsin Dermatology Society Spring Meeting
Keenan TD, Radhakrishnan S, Bell M, Barry M, Pease LR/Keenan TD. (2009, April). Retargeting IgM Antibodies with Different Specificities to a Common Cell Type Reveals Shared Mechanisms Regulating Cellular Activation. Poster presented at: American Association of Immunologists, Immunology 2009; Seattle, WA.
Keenan TD. (May 5 2014) Melanoma Checkpoint Inhibition. Oral Presentation presented at: Wisconsin Dermatology Society Spring meeting
Keenan TD. (Oct 2013) Advances in Melanoma Immunotherapy. Oral Presentation presented at: Advances in Medicine
Keenan TD (April 2013) Presentation of a Novel Lymphomatoid Papulosis Sub-type
Keenan TD. (2009, July). Poly-activating Human IgMs: Divorcing Activity from Specificity. Oral Presentation presented at: Mayo Medical School Annual MSTP Retreat; Owatonna, MN.
Keenan TD. (2008, July). Development of a Peptide Targeting System for the Analysis of Human Monoclonal IgM Therapeutic Antibodies. Oral Presentation presented at: Mayo Graduate School Department of Immunology Annual Retreat; Rochester, MN.
Non Peer Reviewed Online Publication
Keenan TD, Newman JS. (2010, October 1). Arsenic and Olds Lake. http://www.acphospitalist.org/.